Mario Roederer, Ph.D.
Mario Roederer, Ph.D. is a Senior Investigator at the Vaccine Research Center at the National Institutes of Health. Mario has a B.S. in Chemistry from Harvey Mudd College, a Ph.D. in Cell Biology from Carnegie Mellon, and postdoctoral training with Dr. Leonard Herzenberg at Stanford University. As of 2016, he has co-authored more than 300 papers (with 36,000 citations and an h-index >100), five software titles in world-wide use, and eight patents – and was inducted into the Stanford University Invention Hall of Fame.
His research combines advanced technology development in the setting of single cell analysis with basic T and B cell immunology. For more than two decades, he has led the development of sophisticated flow cytometry immunophenotyping technology and data analysis techniques, leading to the state-of-the-art 30+ color analysis and sorting. More recently, the focus of the laboratory has expanded to other single cell technologies, including integration of flow cytometry and high content transcriptomics.
Basic research projects in the laboratory include T cell dynamics during HIV or SIV infection; the definition of the complete repertoire of systemic and mucosal immune functions of elicited by vaccines and pathogens; developing novel vaccine approaches to combat TB, malaria, Zika, and HIV; and defining the genetic and environmental influences on immune homeostasis and autoimmunity.
Adam’s work at Stanford University’s Information Technology Department brought him into contact with the Herzenberg Laboratory, where modern flow cytometry originated. There, he helped with the development of the graphical user interface which made cytometric data analysis practical and later commercialized FlowJo™. Adam has published numerous articles and standards for the flow cytometry community, and while no longer affiliated with FlowJo, LLC, he continues to work on challenges in data integration as a Senior Bioinformatics Engineer at the Gladstone Institutes of UCSF.